Bölüm "AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Biyomühendislik Bölümü" için listeleme
Toplam kayıt 80, listelenen: 21-40
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Computational Prediction of Functional MicroRNA-mRNA Interactions
(HUMANA PRESS INC, 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA, 01.01.2019)Proteins have a strong influence on the phenotype and their aberrant expression leads to diseases. MicroRNAs (miRNAs) are short RNA sequences which posttranscriptionally regulate protein expression. This regulation is ... -
Computational prediction of microRNAs in Histoplasma capsulatum
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND, 2020)MicroRNAs (miRNAs) are small and non-coding RNAs that regulate gene expression through post-transcriptional regulation. Although, the standard miRNA repository, MiRBase, lists more than 200 organisms having miRNA mediated ... -
Computer-Aided Classification of Breast Cancer Histopathological Images
(IEEE345 E 47TH ST, NEW YORK, NY 10017 USA, 2017)Nowadays, one of the most common types of cancer is breast cancer. The early and accurate diagnosis of breast cancer has great importance in the treatment of the disease. In the diagnosis of breast cancer, histopathological ... -
Core-crosslinking as a pathway to develop inherently antibacterial polymeric micelles
(WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019)Positively charged polymeric materials have been an alternative to combat bacteria as they exhibit inherently antibacterial potency via bacteria membrane disruption. In this study, we report facile preparation of positively ... -
A decision support system for the prediction of mortality in patients with acute kidney injury admitted in intensive care unit
(UNIV SOUTH BOHEMIA, FAC HEALTH & SOCIAL STUD, JIROVCOVA, CESKA BUDEJOVICE, 370 04, CZECH REPUBLIC, 2020)Intensive care unit (ICU) is a very special unit of a hospital, where healthcare professionals provide treatment and, later, close followup to the patients. It is crucial to estimate mortality in ICU patients from many ... -
Discovery of adapalene and dihydrotachysterol as antiviral agents for the Omicron variant of SARS‑CoV‑2 through computational drug repurposing
(SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2022)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been signifcantly paralyzing the societies, economies and health care systems around the globe. The mutations on the genome of SARS-CoV-2 led to the emergence ... -
Editorial: Microbial production of medicinally important agents
(FRONTIERS MEDIA SA, 2023)Harnessing microbial systems as bio-factories for the production of medically significant agents presents a thriving avenue in pharmaceutical research. From manufacturing natural products, including potent secondary ... -
The effect of hedgehog inhibition and autophagy modulation on the proliferation and survival of AML cell lines /
(2019)Acute myeloid leukemia (AML) is a heterogeneous hematopoietic malignancy which occurs as a result of many chromosomal abnormalities such as translocations, deletions or insertions. Aberrant signaling pathways such as ... -
Engineered Production of Bioactive Natural Products from Medicinal Plants
(WOLTERS KLUWER MEDKNOW, 2022)Plant natural products have been particularly important due to their use in food, cosmetic, and pharmaceutical industries. In particular, Traditional Chinese Medicine provides a precious potential for the discovery of ... -
Enkapsüle Edilmiş ve Serbest Formda Probiyotik Lactobacillus acidophilus ATCC 4356 Suşunun Dondurma Depolama Periyodunda Stabilitesinin İncelenmesi
(Atatürk Üniversitesi, 2022)Bu çalışmada probiyotik Lb. acidophilus ATCC 4356 (ATCC 4356) suşu, ekstrüzyon yöntemi ile aljinat kullanılarak kapsüllenmiştir. Bu enkapsüle ve serbest formdaki ATCC 4356 dondurmaya ilave edilerek −18°C’de 3 ay süre ile ... -
Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway
(NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2018)Glutamylation is a post-translational modification found on tubulin that can alter the interaction between microtubules (MTs) and associated proteins. The molecular mechanisms regulating tubulin glutamylation in response ... -
Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells
(SPRINGER, 2022)Background Despite the recent advances in chemotherapy, the outcomes and the success of these treatments still remain insufficient. Novel combination treatments and treatment strategies need to be developed in order to ... -
Evaluating the microbial growth kinetics and artificial gastric digestion survival of a novel Pichia kudriavzevii FOL-04
(TAGEM Journals, 2022)Present study aims to explore Pichia kudriavzevii FOL-04 (FOL-04)’s: i) survival against artificial gastric juice (AGJ) and artificial bile juice (ABJ), ii) growth kinetics in shake flask (SF) and fed-batch trials (FBT). ... -
EVALUATION OF THE SENSORY CORRELATION BETWEEN TOUCH SENSITIVITY AND THE CAPACITY TO DISCRIMINATE VISCOSITY
(WILEY, 2015)The capacity to discriminate the viscous nature of food materials is critically important in the sensory evaluation and subsequent perception of food texture and acceptability. It is generally assumed that this capability ... -
Exploring the binding capacity of lactic acid bacteria derived bacteriocins against RBD of SARS-CoV-2 Omicron variant by molecular simulations
(2023)The changes in the SARS-CoV-2 genome have resulted in the emergence of new variants. Some of the variants have been classified as variants of concern (VOC). These strains have higher transmission rate and improved fitness. ... -
Exploring therapeutic avenues: mesenchymal stem/stromal cells and exosomes in confronting enigmatic biofilm-producing fungi
(SPRINGER, 2024)Fungal infections concomitant with bioflms can demonstrate an elevated capacity to withstand substantially higher concentrations of antifungal agents, contrasted with infectious diseases caused by planktonic cells. This ... -
Genomic, probiotic, and metabolic potentials of Liquorilactobacillus nagelii AGA58, a novel bacteriocinogenic motile strain isolated from lactic acid-fermented shalgam
(ELSEVIER, 2023)This study aimed to perform genomic, probiotic, and metabolic characterization of a novel Liquorilactobacillus nagelii AGA58 isolated from a lactic acid-fermented shalgam beverage to understand its metabolic potentials and ... -
HER2-Specific Peptide (LTVSPWY) and Antibody (Herceptin) Targeted Core Cross-Linked Micelles for Breast Cancer: A Comparative Study
(MDPI, 2023)This study aims to prepare a novel breast cancer-targeted micelle-based nanocarrier, which is stable in circulation, allowing intracellular drug release, and to investigate its cytotoxicity, apoptosis, and cytostatic ... -
HER2-Targeted, Degradable Core Cross-Linked Micelles for Specific and Dual pH-Sensitive DOX Release
(WILEY-V C H VERLAG GMBHPOSTFACH 101161, 69451 WEINHEIM, GERMANY, 2021)Here, a targeted, dual-pH responsive, and stable micelle nanocarrier is designed, which specifically selects an HER2 receptor on breast cancer cells. Intracellularly degradable and stabilized micelles are prepared by core ... -
Histopathology image classification: highlighting the gap between manual analysis and AI automation
(FRONTIERS MEDIA SA, 2023)The field of histopathological image analysis has evolved significantly with the advent of digital pathology, leading to the development of automated models capable of classifying tissues and structures within diverse ...