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Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
Bakır Güngör, Burcu; Ünlü, Yazıcı, Miray; Göy, Gökhan; Temiz, Mustafa (TUBITAK, 2022)Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ... -
Investigation of interaction between nanocrystal quantum dot films and escherichia coli
Ünlü, Miray (Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2017)Semiconductor nanocrytals also known as quantum dots (QD) with high photoluminesce quantum yield (PLQY), size tunability and favorable optical characteristics occupy a significant area in display technology, solar energy ... -
miRcorrNetPro: Unraveling Algorithmic Insights through Cross-Validation in Multi-Omics Integration for Comprehensive Data Analysis
Yazici, Miray Unlu; Yousef, Malik; Marron J.S.; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2023)High throughput -omics technologies facilitate the investigation of regulatory mechanisms of complex diseases. Along this line, scientists develop promising tools and methods to extend our understanding at the molecular ... -
A Top-Down Approach for Finding Affected Pathway Subnetworks in Type 2 Diabetes
Unlu Yazici, Miray; Bakir-Gungor, Burcu (IEEE, 2020)Diyabet (Diabetes Mellitus, DM), insülin üreten pankreas beta hücrelerindeki fonksiyon bozukluğu, insülin direnci veya insülinin işlevselliğinin bozulması ile meydana gelen bir tür metabolik bozukluktur. Diyabet vakalarının ...