Browsing by Author "Bakir-Gungor, Burcu"
Now showing items 1-20 of 51
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Active Subnetwork GA: A Two Stage Genetic Algorithm Approach to Active Subnetwork Search
Ozisik, Ozan; Bakir-Gungor, Burcu; Diri, Banu; Sezerman, Osman Ugur (BENTHAM SCIENCE PUBL LTDEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, 2017)Background: A group of interconnected genes in a protein-protein interaction network that contains most of the disease associated genes is called an active subnetwork. Active subnetwork search is an NP-hard problem. In the ... -
Aguhyper: a hyperledger-based electronic health record management framework
Dedeturk, Beyhan Adanur; Bakir-Gungor, Burcu (PEERJ INC, 2024)The increasing importance of healthcare records, particularly given the emergence of new diseases, emphasizes the need for secure electronic storage and dissemination. With these records dispersed across diverse healthcare ... -
AMP-GSM: Prediction of Antimicrobial Peptides via a Grouping–Scoring–Modeling Approach
Soylemez, Ummu Gulsum; Yousef, Malik; Bakir-Gungor, Burcu (MDPI, 2023)Due to the increasing resistance of bacteria to antibiotics, scientists began seeking new solutions against this problem. One of the most promising solutions in this field are antimicrobial peptides (AMP). To identify ... -
Application of Biological Domain Knowledge Based Feature Selection on Gene Expression Data
Yousef, Malik; Kumar, Abhishek; Bakir-Gungor, Burcu (MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021)In the last two decades, there have been massive advancements in high throughput technologies, which resulted in the exponential growth of public repositories of gene expression datasets for various phenotypes. It is ... -
Blockchain-based Fog Computing Applications in Healthcare
Adanur, Beyhan; Bakir-Gungor, Burcu; Soran, Ahmet (IEEE, 2020)— Son zamanlarda blokzincir teknolojisinin sağlık alanında kullanımı artmıştır. Blokzincir teknolojisinin sağlık alanına getirdiği birçok yenilik olmasına rağmen, halen çözülmeyi bekleyen problemleri mevcuttur. Bu ... -
CCPred: Global and population-specific colorectal cancer prediction and metagenomic biomarker identification at different molecular levels using machine learning techniques
Bakir-Gungor, Burcu; Temiz, Mustafa; Inal, Yasin; Cicekyurt, Emre; Yousef, Malik (ELSEVIER, 2024)Colorectal cancer (CRC) ranks as the third most common cancer globally and the second leading cause of cancer-related deaths. Recent research highlights the pivotal role of the gut microbiota in CRC development and ... -
Classification of Breast Cancer Molecular Subtypes with Grouping-Scoring-Modeling Approach that Incorporates Disease-Disease Association Information
Qumsiyeh, Emma; Bakir-Gungor, Burcu; Yousef, Malik (IEEE Xplore, 2024)This study uses modern sequencing technology and large biological databases to investigate the molecular intricacies of complicated diseases like cancer. Using gene expression databases and biomarkers, the research aims ... -
A comparative study on psychiatric disorders: Identification of shared pathways and common agents
Kuzudisli, Cihan; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2022)Distinct but closely related diseases generally present shared symptoms, which address possible overlaps among their pathogenic mechanisms. Identification of significantly impacted shared pathways and other common agents ... -
CSA-DE-LR: enhancing cardiovascular disease diagnosis with a novel hybrid machine learning approach
Dedeturk, Beyhan Adanur; Dedeturk, Bilge Kagan; Bakir-Gungor, Burcu (PEERJ INC, 2024)Cardiovascular diseases (CVD) are a leading cause of mortality globally, necessitating the development of efficient diagnostic tools. Machine learning (ML) and metaheuristic algorithms have become prevalent in addressing ... -
The Determination of Distinctive Single Nucleotide Polymorphism Sets for the Diagnosis of Behçet's Disease
Isik, Yunus EMRE; Gormez, Yasin; Aydin, Zafer; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2021)Behçet's Disease (BD) is a multi-system inflammatory disorder in which the etiology remains unclear. The most probable hypothesis is that genetic tendency and environmental factors play roles in the development of BD. In ... -
Developing a label propagation approach for cancer subtype classification problem
Guner, Pinar; Bakir-Gungor, Burcu; Coskun, Mustafa (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYATATURK BULVARI NO 221, KAVAKLIDERE, ANKARA 00000, TURKEY, 2022)Cancer is a disease in which abnormal cells grow uncontrollably and invade other tissues. Several types of cancer have various subtypes with different clinical and biological implications. Based on these differences, ... -
Discovering Potential Taxonomic Biomarkers of Type 2 Diabetes From Human Gut Microbiota via Different Feature Selection Methods
Bakir-Gungor, Burcu; Bulut, Osman; Jabeer, Amhar; Nalbantoglu, O. Ufuk; Yousef, Malik (FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021)Human gut microbiota is a complex community of organisms including trillions of bacteria. While these microorganisms are considered as essential regulators of our immune system, some of them can cause several diseases. In ... -
The Effect of Different Classifiers on Recursive Cluster Elimination in the Analysis of Transcriptomic Data
Bulut, Nurten; Bakir-Gungor, Burcu; Qaqish, Bahjat F.; Yousef, Malik (Institute of Electrical and Electronics Engineers Inc., 2023)Gene expression data with limited sample size and a large number of genes are frequently encountered in genetic studies. In such high-dimensional data, identification of genes that distinguish between disease states is ... -
Effect of Recursive Cluster Elimination with Different Clustering Algorithms Applied to Gene Expression Data
Kuzudisli, Cihan; Bakir-Gungor, Burcu; Qaqish, Bahjat F.; Yousef, Malik. (Institute of Electrical and Electronics Engineers Inc., 2023)Feature selection (FS) is an effective tool in dealing with high dimensionality and reducing computational cost. Support Vector Machines – Recursive Cluster Elimination (SVM-RCE) is one of several algorithms that have ... -
Ensemble feature selection and classification methods for machine learning-based coronary artery disease diagnosis
Kolukisa, Burak; Bakir-Gungor, Burcu (ELSEVIER, 2023)Coronary artery disease (CAD) is a condition in which the heart is not fed sufficiently as a result of the accumulation of fatty matter. As reported by the World Health Organization, around 32% of the total deaths in the ... -
Ensemble Feature Selection for Clustering Damage Modes in Carbon Fiber-Reinforced Polymer Sandwich Composites Using Acoustic Emission
Gulsen, Abdulkadir; Kolukisa, Burak; Caliskan, Umut; Bakir-Gungor, Burcu; Gungor, Vehbi Cagri (John Wiley and Sons Inc, 2024)Acoustic emission (AE) serves as a noninvasive technique for real-time structural health monitoring, capturing the stress waves produced by the formation and growth of cracks within a material. This study presents a novel ... -
eTNT: Enhanced TextNetTopics with Filtered LDA Topics and Sequential Forward / Backward Topic Scoring Approaches
Voskergian, Daniel; Jayousi, Rashid; Bakir-Gungor, Burcu (SCIENCE & INFORMATION-SAI ORGANIZATION LTD, 2024)TextNetTopics is a novel text classification-based topic modelling approach that focuses on topic selection rather than individual word selection to train a machine learning algorithm. However, one key limitation of ... -
Evaluation of Classification Algorithms, Linear Discriminant Analysis and a New Hybrid Feature Selection Methodology for the Diagnosis of Coronary Artery Disease
Kolukisa, Burak; Hacilar, Hilal; Goy, Gokhan; Kus, Mustafa; Bakir-Gungor, Burcu; Aral, Atilla); Gungor, Vehbi Cagri (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)According to the World Health Organization (WHO), 31% of the world's total deaths in 2016 (17.9 million) was due to cardiovascular diseases (CVD). With the development of information technologies, it has become possible ... -
GeNetOntology: identifying affected gene ontology terms via grouping, scoring, and modeling of gene expression data utilizing biological knowledge-based machine learning
Ersoz, Nur Sebnem; Bakir-Gungor, Burcu; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Introduction: Identifying significant sets of genes that are up/downregulated under specific conditions is vital to understand disease development mechanisms at the molecular level. Along this line, in order to analyze ... -
Graph-based Biomedical Knowledge Discovery
Altuner, Osman; Bakir-Gungor, Burcu; Bakal, Gokhan (IEEE, 2024)Dijitalleşme süreci tüm dünyada oldukça yüksek bir hızla ilerlemektedir. Bu durum günümüz yaşantısında bir çok kolaylık sağladığı gibi ortaya çıkan devasa dijital verilerin analizi ve işlenmesi gibi bir problemi de ...
