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Machine learning based classifcation of cells into chronological stages using singlecell transcriptomics

Singh, Sumeet Pal; Janjuha, Sharan; Chaudhuri, Samata; Reinhardt, Susanne; Kränkel, Annekathrin; Dietz, Sevina; Eugster, Anne; Bilgin, Halil; Korkmaz, Selçuk; Zararsız, Gökmen; Ninov, Nikolay; Reid, John E. (NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2018)

Age-associated deterioration of cellular physiology leads to pathological conditions. The ability to detect premature aging could provide a window for preventive therapies against age-related diseases. However, the techniques ...