Browsing by Author "Topuzogullari, Murat"
Now showing items 1-3 of 3
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Core-crosslinking as a pathway to develop inherently antibacterial polymeric micelles
Kadayifci, Melike Seyma; Gokkaya, Damla; Topuzogullari, Murat; Isoglu, Sevil Dincer; Atabey, Tugba; Arasoglu, Tulin; Ozmen, Mehmet Murat (WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 01.08.2019)Positively charged polymeric materials have been an alternative to combat bacteria as they exhibit inherently antibacterial potency via bacteria membrane disruption. In this study, we report facile preparation of positively ... -
A new approach for development of vaccine against visceral leishmaniasis: Lipophosphoglycan and polyacrylic acid conjugates
Allahverdiyev, Adil M.; Koc, Rabia Cakir; Bagirova, Melahat; Elcicek, Serhat; Yesilkir Baydar, Serap; Oztel, Olga Nehir; Abamor, Emrah Sefik; Ates, Sezen Canim; Topuzogullari, Murat; Dincer, Sevil Isoglu; Akdeste, Zeynep (ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2017)Objective: To determine the antileishmanial vaccine effectiveness of lipophosphoglycan (LPG) and polyacrylic acids (PAA) conjugates on in vivo mice models. Methods: LPG molecule was isolated and purified from large-scale ... -
pH- and temperature-responsive amphiphilic diblock copolymers of 4-vinylpyridine and oligoethyleneglycol methacrylate synthesized by RAFT polymerization
Topuzogullari, Murat; Bulmus, Volga; Dalgakiran, Eray; Dincer, Sevil (ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2014)Diblock copolymers of 4-vinylpyridine (4VP) and oligoethyleneglycol methyl ether methacrylate (OEGMA) were synthesized for the first time using RAFT polymerization technique as potential drug delivery systems. Effects of ...