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Toplam kayıt 7, listelenen: 1-7
HomSI: a homozygous stretch identifier from next-generation sequencing data
(OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND, 2014)
In consanguineous families, as a result of inheriting the same genomic segments through both parents, the individuals have stretches of their genomes that are homozygous. This situation leads to the prevalence of recessive ...
PANOGA: a web server for identification of SNP-targeted pathways from genome-wide association study data
(OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND, 2014)
Genome-wide association studies (GWAS) have revolutionized the search for the variants underlying human complex diseases. However, in a typical GWAS, only a minority of the single-nucleotide polymorphisms (SNPs) with the ...
Identification of possible pathogenic pathways in Behcet's disease using genome-wide association study data from two different populations
(NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2015)
Behcet's disease (BD) is a multi-system inflammatory disorder of unknown etiology. Two recent genome-wide association studies (GWASs) of BD confirmed a strong association with the MHC class I region and identified two ...
Machine Learning Analysis of Inflammatory Bowel Disease-Associated Metagenomics Dataset
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)
There is an ongoing interplay between humans and our microbial communities. The microorganisms living in our gut produce energy from our food, strengthen our immune system, break down foreign products, and release metabolites ...
Identify Commonly Affected Pathways in Psychiatric Diseases
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)
Genome-wide association studies (GWAS) are an extraordinary source of information when it comes to revealing the common variations of human complex diseases. Until now, the large amount of data generated from these studies ...
Evaluation of Classification Algorithms, Linear Discriminant Analysis and a New Hybrid Feature Selection Methodology for the Diagnosis of Coronary Artery Disease
(IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)
According to the World Health Organization (WHO), 31% of the world's total deaths in 2016 (17.9 million) was due to cardiovascular diseases (CVD). With the development of information technologies, it has become possible ...
Active Subnetwork GA: A Two Stage Genetic Algorithm Approach to Active Subnetwork Search
(BENTHAM SCIENCE PUBL LTDEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, 2017)
Background: A group of interconnected genes in a protein-protein interaction network that contains most of the disease associated genes is called an active subnetwork. Active subnetwork search is an NP-hard problem. In the ...