Yazar "0000-0002-2272-6270" için Yaşam ve Doğa Bilimleri Fakültesi listeleme
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Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
Bakır Güngör, Burcu; Ünlü, Yazıcı, Miray; Göy, Gökhan; Temiz, Mustafa (TUBITAK, 2022)Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ... -
GeNetOntology: identifying affected gene ontology terms via grouping, scoring, and modeling of gene expression data utilizing biological knowledge-based machine learning
Ersoz, Nur Sebnem; Bakir-Gungor, Burcu; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Introduction: Identifying significant sets of genes that are up/downregulated under specific conditions is vital to understand disease development mechanisms at the molecular level. Along this line, in order to analyze ... -
Identifying Taxonomic Biomarkers of Colorectal Cancer in Human Intestinal Microbiota Using Multiple Feature Selection Methods
Jabeer, Amhar; Kocak, Aysegul; Akkas, Huseyin; Yenisert, Ferhan; Nalbantoglu, Ozkan Ufuk; Yousef, Malik; Bakir Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2022)A variety of bacterial species called gut microbiota work together to maintain a steady intestinal environment. The gastrointestinal tract contains tremendous amount of different species including archaea, bacteria, fungi, ... -
miRcorrNetPro: Unraveling Algorithmic Insights through Cross-Validation in Multi-Omics Integration for Comprehensive Data Analysis
Yazici, Miray Unlu; Yousef, Malik; Marron J.S.; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2023)High throughput -omics technologies facilitate the investigation of regulatory mechanisms of complex diseases. Along this line, scientists develop promising tools and methods to extend our understanding at the molecular ... -
A Top-Down Approach for Finding Affected Pathway Subnetworks in Type 2 Diabetes
Unlu Yazici, Miray; Bakir-Gungor, Burcu (IEEE, 2020)Diyabet (Diabetes Mellitus, DM), insülin üreten pankreas beta hücrelerindeki fonksiyon bozukluğu, insülin direnci veya insülinin işlevselliğinin bozulması ile meydana gelen bir tür metabolik bozukluktur. Diyabet vakalarının ...