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Toplam kayıt 55, listelenen: 21-30
Deep learning based semantic segmentation and quantification for MRD biochip images
(ELSEVIER SCI LTD, 2022)
Microfluidic platforms offer prominent advantages for the early detection of cancer and monitoring the patient
response to therapy. Numerous microfluidic platforms have been developed for capturing and quantifying the
tumor ...
Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells
(SPRINGER, 2022)
Background Despite the recent advances in chemotherapy, the outcomes and the success of these treatments still remain insufficient. Novel combination treatments and treatment strategies need to be developed in order to ...
Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cells
(ELSEVIER, 2023)
In this study, it was aimed to elucidate the interaction between aryl hydrocarbon receptor (AHR), nuclear factor -kappa B (NF-kB), and cytochrome P4501A1 (CYP1A1) with hepatitis B virus X protein (HBX) in a human liver ...
Differential in vitro anti-leukemic activity of resveratrol combined with serine palmitoyltransferase inhibitor myriocin in FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) carrying AML cells
(SPRINGER, 2022)
Treatment of FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) AML is restricted due to toxicity, drug resistance and relapse eventhough targeted therapies are clinically available. Resveratrol with its ...
TACTILE SENSITIVITY and CAPABILITY OF SOFT-SOLID TEXTURE DISCRIMINATION
(WILEY, 2015)
The sensation and perception of food texture is regulated by tactile-dominated
mechanisms and therefore, it is believed that one’s capability in discriminating
food textural properties could be related to one’s tactile ...
A Top-Down Approach for Finding Affected Pathway Subnetworks in Type 2 Diabetes
(IEEE, 2020)
Diyabet (Diabetes Mellitus, DM), insülin üreten
pankreas beta hücrelerindeki fonksiyon bozukluğu, insülin direnci
veya insülinin işlevselliğinin bozulması ile meydana gelen bir tür
metabolik bozukluktur. Diyabet vakalarının ...
Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors
(SPRINGER BIRKHAUSER, 2023)
In this study, a total of 13 compounds (5-17) were synthesized starting from oleanolic acid (OA), a natural triterpenoid. Five new compounds (10, 11, 12, 15 and 17), are the main targets of the study, which were synthesized ...
NeRNA: A negative data generation framework for machine learning applications of noncoding RNAs
(PERGAMON-ELSEVIER SCIENCE, 2023)
Many supervised machine learning based noncoding RNA (ncRNA) analysis methods have been developed to
classify and identify novel sequences. During such analysis, the positive learning datasets usually consist of
known ...
RAFT-mediated synthesis of poly(N-(2-hydroxypropyl)methacrylamide-b-4-vinylpyridine) by conventional and microwave heating
(SPRINGERONE NEW YORK PLAZA, SUITE 4600 , NEW YORK, NY 10004, UNITED STATES, 2013)
We report the synthesis of N-(2-hydroxypropyl)methacrylamide
(HPMA) macroCTA and HPMA-b-4-Vinylpyridine block copolymers via reversible
addition-fragmentation chain transfer (RAFT) reaction. Polymerization was carried
out ...
Polyethylenimine Modified and Non-Modified Polymeric Micelles Used for Nasal Administration of Carvedilol
(AMER SCIENTIFIC PUBLISHERS, 2015)
This study evaluates the ability of polyethylenimine-modified and non-modified polymeric micelles to enhance permeation through the nasal mucosa for a highly hydrophobic model drug. Carvedilol was loaded into polyethylen ...