Yazar "Bakir-Gungor, Burcu" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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Integrative analyses in omics data: Machine learning perspective
Yazici, Miray Unlu; Bakir-Gungor, Burcu; Yousef, Malik (Deutsche Gesellschaft fur Medizinische Informatik, Biometrie und Epidemiologie e.V., 2023)Developments in the high throughput technologies have enabled the production of an immense amount of knowledge at the multi-omics level. Considering complex diseases which are affected by multi-factors, single omics datasets ... -
Invention of 3Mint for feature grouping and scoring in multi-omics
Yazici, Miray Unlu; Marron, J. S.; Bakir-Gungor, Burcu; Zou, Fei; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Advanced genomic and molecular profiling technologies accelerated the enlightenment of the regulatory mechanisms behind cancer development and progression, and the targeted therapies in patients. Along this line, intense ... -
Machine Learning Analysis of Inflammatory Bowel Disease-Associated Metagenomics Dataset
Hacilar, Hilal; Nalbantoglu, O. Ufuk; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)There is an ongoing interplay between humans and our microbial communities. The microorganisms living in our gut produce energy from our food, strengthen our immune system, break down foreign products, and release metabolites ... -
microBiomeGSM: the identification of taxonomic biomarkers from metagenomic data using grouping, scoring and modeling (G-S-M) approach
Bakir-Gungor, Burcu; Temiz, Mustafa; Jabeer, Amhar; Wu, Di; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Numerous biological environments have been characterized with the advent of metagenomic sequencing using next generation sequencing which lays out the relative abundance values of microbial taxa. Modeling the human microbiome ... -
miRcorrNetPro: Unraveling Algorithmic Insights through Cross-Validation in Multi-Omics Integration for Comprehensive Data Analysis
Yazici, Miray Unlu; Yousef, Malik; Marron J.S.; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2023)High throughput -omics technologies facilitate the investigation of regulatory mechanisms of complex diseases. Along this line, scientists develop promising tools and methods to extend our understanding at the molecular ... -
miRdisNET: Discovering microRNA biomarkers that are associated with diseases utilizing biological knowledge-based machine learning
Jabeer, Amhar; Temiz, Mustafa; Bakir-Gungor, Burcu; Yousef, Malik (Frontiers Media S.A., 2023)During recent years, biological experiments and increasing evidence have shown that microRNAs play an important role in the diagnosis and treatment of human complex diseases. Therefore, to diagnose and treat human complex ... -
Multi fragment melting analysis system (MFMAS) for one-step identification of lactobacilli
Kesmen, Zulal; Kilic, Ozge; Gormez, Yasin; Celik, Mete; Bakir-Gungor, Burcu (ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS, 2020)The accurate identification of lactobacilli is essential for the effective management of industrial practices associated with lactobacilli strains, such as the production of fermented foods or probiotic supplements. For ... -
PANOGA: a web server for identification of SNP-targeted pathways from genome-wide association study data
Bakir-Gungor, Burcu; Egemen, Ece; Sezerman, Osman Ugur (OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND, 2014)Genome-wide association studies (GWAS) have revolutionized the search for the variants underlying human complex diseases. However, in a typical GWAS, only a minority of the single-nucleotide polymorphisms (SNPs) with the ... -
Performance Evaluations of Active Subnetwork Search Methods in Protein-Protein Interaction Networks
Gunter, Pinar; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 01.01.2019)Protein-protein interaction networks are mathematical representations of the physical contacts between proteins in the cell. A group of interconnected proteins in a protein-protein interaction network that contains most ... -
Population Specific Classification of Colorectal Cancer with Meta-Analysis of Metagenomic Data
Temiz, Mustafa; Yousef, Malik; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2023)Yeni nesil dizilemedeki ve "-omik" teknolojilerdeki gelişmeler, insan bağırsak mikrobiyomunu karakterize etmeyi mümkün kılmaktadır. Bu mikroorganizmaların bazıları bağışıklık sistemimizin temel düzenleyicileriyken, ... -
PriPath: identifying dysregulated pathways from differential gene expression via grouping, scoring, and modeling with an embedded feature selection approach
Yousef, Malik; Ozdemir, Fatma; Jaber, Amhar; Allmer, Jens; Bakir-Gungor, Burcu (BMC, 2023)BackgroundCell homeostasis relies on the concerted actions of genes, and dysregulated genes can lead to diseases. In living organisms, genes or their products do not act alone but within networks. Subsets of these networks ... -
The relationship between PAPP-A levels, maternal characteristics, gestational diabetes and other biochemical markers of the aneuploidy screening
Uzut, Ommu Gulsum; Celebiler, Hande Kaymakcalan; Harkonen, Juho; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)First trimester aneuploidy screening is routinely used in pregnancy follow-ups. In this screening, free /l-hCG and pregnancy-associated plasma protein A (PAPP-A) levels in the blood of the pregnant woman arc measured. The ... -
The relationship between TSH levels, maternal characteristics and racial group of the aneuploidy screening
Soylemez, Ummu Gulsum; Celebiler, Hande Kaymakcalan; Harkonen, Juho; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2022)First-trimester maternal screening is a widely used test for detecting fetal aneuploidies and neural tube defects for over two decades. Human chorionic gonadotropin hormone (beta-hCG) and pregnancy-associated plasma protein ... -
Review of feature selection approaches based on grouping of features
Kuzudisli, Cihan; Bakir-Gungor, Burcu; Bulut, Nurten; Qaqish, Bahjat; Yousef, Malik (PeerJ Inc., 2023)With the rapid development in technology, large amounts of high-dimensional data have been generated. This high dimensionality including redundancy and irrelevancy poses a great challenge in data analysis and decision ... -
Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
Bakir-Gungor, Burcu; Moreno-Indias, Isabel; Lahti, Leo; Nedyalkova, Miroslava; Elbere, Ilze; Roshchupkin, Gennady; Adilovic, Muhamed; Aydemir, Onder; Santa Pau, Enrique Carrillo-de; D'Elia, Domenica; Desai, Mahesh S.; Falquet, Laurent; Gundogdu, Aycan; Hron, Karel; Klammsteiner, Thomas; Lopes, Marta B.; Marcos-Zambrano, Laura Judith; Marques, Claudia; Mason, Michael; May, Patrick; Pasic, Lejla; Pio, Gianvito; Pongor, Sandor; Promponas, Vasilis J.; Przymus, Piotr; Saez-Rodriguez, Julio; ampri, Alexia; Shigdel, Rajesh; Stres, Blaz; Suharoschi, Ramona; Truu, Jaak; Truica, Ciprian-Octavian; Vilne, Baiba; Vlachakis, Dimitrios; Yilmaz, Ercument; Zeller, Georg; Zomer, Aldert L.; Gomez-Cabrero, David; Claesson, Marcus J. (FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021)The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many ... -
SVM-RCE-R-OPT: Optimization of Scoring Function for SVM-RCE-R
Yousef, Malik; Jabeer, Amhar; Bakir-Gungor, Burcu (SPRINGER INTERNATIONAL PUBLISHING AGGEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND, 2021)Gene expression data classification provides a challenge in classification due to it having high dimensionality and a relatively small sample size. Different feature selection approaches have been used to overcome this ... -
SYNE1 related cerebellar ataxia presents with variable phenotypes in a consanguineous family from Turkey
Yucesan, E.; Iseri, Sibel A. Ugur; Bilgic, B.; Gormez, Z.; Gungor, B. Bakir; Sarac, A.; Ozdemir, O.; Sagiroglu, M.; Gurvit, H.; Hanagasi, H.; Ozbek, U. (SPRINGER-VERLAG ITALIA SRLVIA DECEMBRIO, 28, MILAN 20137, ITALY, 2017)SYNE1 related autosomal recessive cerebellar ataxia type 1 (ARCA1) is a late-onset cerebellar ataxia with slow progression originally demonstrated in French-Canadian populations of Quebec, Canada. Nevertheless, recent ... -
TextNetTopics Pro, a topic model-based text classification for short text by integration of semantic and document-topic distribution information
Voskergian, Daniel; Bakir-Gungor, Burcu; Yousef, Malik (FRONTIERS MEDIA SA, 2023)With the exponential growth in the daily publication of scientific articles, automatic classification and categorization can assist in assigning articles to a predefined category. Article titles are concise descriptions ... -
A toolbox of machine learning software to support microbiome analysis
Marcos-Zambrano, Laura Judith; López-Molina, Víctor Manuel; Bakir-Gungor, Burcu; Frohme, Marcus; Karaduzovic-Hadziabdic, Kanita; Klammsteiner, Thomas; Ibrahimi, Eliana; Lahti, Leo; Loncar-Turukalo, Tatjana; Dhamo, Xhilda; Simeon, Andrea; Nechyporenko, Alina; Pio, Gianvito; Przymus, Piotr; Sampri, Alexia; Trajkovik, Vladimir; Lacruz-Pleguezuelos, Blanca; Aasmets, Oliver; Araujo, Ricardo; Anagnostopoulos, Ioannis; Aydemir, Önder; Berland, Magali; Calle, M. Luz; Ceci, Michelangelo; Duman, Hatice; Gündoğdu, Aycan; Havulinna, Aki S.; Kaka Bra; Kardokh Hama Najib; Kalluci, Eglantina; Karav, Sercan; Lode, Daniel; Lopes, Marta B.; May, Patrick; Nap, Bram; Nedyalkova, Miroslava; Paciência, Inês; Pasic, Lejla; Pujolassos, Meritxell; Shigdel, Rajesh; Susín, Antonio; Thiele, Ines; Truică, Ciprian-Octavian; Wilmes, Paul; Yilmaz, Ercument; Yousef, Malik; Claesson, Marcus Joakim; Truu, Jaak; Carrillo de Santa Pau, Enrique (Frontiers Media SA, 2023)The human microbiome has become an area of intense research due to its potential impact on human health. However, the analysis and interpretation of this data have proven to be challenging due to its complexity and ... -
A Top-Down Approach for Finding Affected Pathway Subnetworks in Type 2 Diabetes
Unlu Yazici, Miray; Bakir-Gungor, Burcu (IEEE, 2020)Diyabet (Diabetes Mellitus, DM), insülin üreten pankreas beta hücrelerindeki fonksiyon bozukluğu, insülin direnci veya insülinin işlevselliğinin bozulması ile meydana gelen bir tür metabolik bozukluktur. Diyabet vakalarının ...