Yazar "Akcok, Emel Basak Gencer" için listeleme
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Determination of promising inhibitors for N-SH2 domain of SHP2 tyrosine phosphatase: an in silico study
Akcok, Emel Basak Gencer; Guner, Huseyin; Akcok, Ismail (SPRINGER NATURE LINK, 2024)There are many genes that produce proteins related to diseases and these proteins can be targeted with drugs as a potential therapeutic approach. Recent advancement in drug discovery techniques have created new opportunities ... -
Histone Deacetylase Inhibition and Autophagy Modulation Induces a Synergistic Antiproliferative Effect and Cell Death in Cholangiocarcinoma Cells
Yenigul, Munevver; Akcok, Emel Basak Gencer (AMER CHEMICAL SOC, 2023)Cholangiocarcinoma, also known as biliary tract cancer,is an aggressiveadenocarcinoma arising from epithelial cells lining the intra- andextrahepatic biliary system. The effects of autophagy modulators andhistone deacetylase ... -
Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells
Subay, Lale Beril; Akcok, Emel Basak Gencer; Akcok, Ismail (SPRINGER NATURE LINK, 2025)BackgroundAcute myeloid leukemia (AML) is a heterogeneous hematological malignancy caused by disorders in stem cell differentiation and excessive proliferation resulting in clonal expansion of dysfunctional cells called ...
