Yazar "0000-0002-0947-6166" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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Automated quantification of immunomagnetic beads and leukemia cells from optical microscope images
Uslu, Fatma; Icoz, Kutay); Tasdemir, Kasim; Yilmaz, Bulent (ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2019)Quantification of tumor cells is crucial for early detection and monitoring the progress of cancer. Several methods have been developed for detecting tumor cells. However, automated quantification of cells in the presence ... -
Deep learning based semantic segmentation and quantification for MRD biochip images
Çelebi, Fatma; Tasdemir, Kasim; Icoz, Kutay (ELSEVIER SCI LTD, 2022)Microfluidic platforms offer prominent advantages for the early detection of cancer and monitoring the patient response to therapy. Numerous microfluidic platforms have been developed for capturing and quantifying the tumor ... -
Design, modeling, and control of a horizontal magnetic micromanipulator
Ablay, Gunyaz; Boyuk, Mustafa; Icoz, Kutay (SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019)Magnetic micromanipulators with a wide range of force generating capabilities are able to manipulate micron size particles for various applications and measurements. These magnetic particles can be coated with receptors ... -
Feedback controller designs for an electromagnetic micromanipulator
Boyuk, Mustafa; Eroglu, Yakup; Ablay, Gunyaz; Icoz, Kutay (SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019)Magnetic micromanipulators are capable of generating wide range of magnetic forces to manipulate magnetic microparticles for biomedical applications. In this study, a multipole magnetic micromanipulator system including ... -
High spatial resolution IoT based air PM measurement system
Icoz, Ebru; Malik, Fasih M.; Icoz, Kutay (SPRINGERVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2021)Air pollution is one of the global problems of the current era. According to World Health Organization more than 80% of the people living in metropolitan areas breathe air which exceeds the guideline limits. Particulate ... -
A horizontal magnetic tweezer for single molecule micromanipulations
Ablay, Gunyaz; Boyuk, Mustafa; Eroglu, Yakup; Icoz, Kutay (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)Magnetic tweezers are able to manipulate cells or biomolecules for various applications and measurements. In this work, a horizontal magnetic tweezer is designed, modeled and controlled for single molecule manipulations. ... -
Image-analysis based readout method for biochip: Automated quantification of immunomagnetic beads, micropads and patient leukemia cell
Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim; Dogan, Refika S.; Yilmaz, Bulent (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2020)For diagnosing and monitoring the progress of cancer, detection and quantification of tumor cells is utmost important. Beside standard bench top instruments, several biochip-based methods have been developed for this ... -
Image-Processing Based Signal Readout Method for MRD Biochip
Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2019)The response of the cancer patients to chemotherapy treatment varies from person to person. For some patients cancer cells are resistant to treatment and these cells can relapse again which is known as minimal residual ... -
Immunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements
Icoz, Kutay; Eken, Ahmet; Cinar, Suzan; Murat, Aysegul; Ozcan, Servet; Unal, Ekrem; Deniz, Gunnur (TAYLOR & FRANCIS INC, 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA, 2020)In order to detect the blast cells from bone marrow of patients, one strategy is to first isolate the cells using immunomagnetic beads. The aim of this study was to report the experimental results of the immunomagnetic ... -
Improved senescent cell segmentation on bright-field microscopy images exploiting representation level contrastive learning
Çelebi, Fatma; Boyvat, Dudu; Ayaz-Guner, Serife; Tasdemir, Kasim; Icoz, Kutay (WILEY Online Library, 2024)Mesenchymal stem cells (MSCs) are stromal cells which have multi-lineage differentiation and self-renewal potentials. Accurate estimation of total number of senescent cells in MSCs is crucial for clinical applications. ... -
Magnetic Separation of Micro Beads and Cells on a Paper-Based Lateral Flow System
Farooqi, Muhammed Fuad; Icoz, Kutay (GAZİ ÜNİVERSİTESİ, 2023)Paper based lateral flow systems are widely used biosensor platforms to detect biomolecules in a liquid sample. Proteins, bacteria, oligonucleotides, and nanoparticles were investigated in the literature. In this work ... -
Microfluidic Chip based direct triple antibody immunoassay for monitoring patient comparative response to leukemia treatment
Icoz, Kutay; Akar, Unal; Unal, Ekrem (SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2020)We report a time and cost-efficient microfluidic chip for screening the leukemia cells having three specific antigens. In this method, the target blast cells are double sorted with immunomagnetic beads and captured by the ... -
Molecular Separation by Using Active and Passive Microfluidic chip Designs: A Comprehensive Review
Ebrahimi, Aliakbar; Icoz, Kutay; Didarian, Reza; Shih, Chih-Hsin; Tarim, E. Alperay; Nasseri, Behzad; Akpek, Ali; Cecen, Berivan; Bal-Ozturk, Ayca; Güleç, Kadri; Li, Yi-Chen Ethan; Shih, Steven; Sirma Tarim, Burcu; Tekin, H. Cumhur; Tayybi-Azar, Mehdi; Ghorbanpoor, Hamed; Özel, Ceren; Eker Sarıboyacı, Ayla; Dogan Guzel, Fatma; Bassous, Nicole; Shin, Su Ryon; Avci, Huseyin; Alarçin, Emine (John Wiley and Sons Inc, 2024)Separation and identification of molecules and biomolecules such as nucleic acids, proteins, and polysaccharides from complex fluids are known to be important due to unmet needs in various applications. Generally, many ... -
Numerical analysis and experimental verification of optical scattering from microplastics
Genc, Sinan; Icoz, Kutay; Erdem, Talha (ROYAL SOC, 2023)Accurate and fast characterization of the micron-sized plastic particles in aqueous media requires an in-depth understanding of light interaction with these particles. Due to the complexity of Mie scattering theory, the ... -
On-demand weighing of single dry biological particles over a 5-order-of-magnitude dynamic range
Chan, Bin-Da; Huang, Wanfeng; Chang, Chun-Li; Savran, Cagri A.; Icoz, Kutay (ROYAL SOC CHEMISTRY, 2014)We report a simple and highly versatile system to select and weigh individual dry biological particles. The system is composed of a microtweezer to pick and place individual particles and a cantilever-based resonator to ... -
Optical detection of microplastics in water
Iri, Ahmet H.; Shahrah, Malek H. A.; Ali, Ali M.; Qadri, Sayed A.; Erdem, Talha; Ozdur, Ibrahim T.; Icoz, Kutay (SPRINGER HEIDELBERGTIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, 2021)Unfortunately, the plastic pollution increases at an exponential rate and drastically endangers the marine ecosystem. According to World Health Organization (WHO), microplastics in drinking water have become a concern and ... -
Parameter investigation of topological data analysis for EEG signals
Altindis, Fatih; Yilmaz, Bulent; Borisenok, Sergey; Icoz, Kutay (ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 01.01.2021)Topological data analysis (TDA) methods have become appealing in EEG signal processing, because they may help the scientists explore new features of complex and large amount of data by simplifying the process from a ... -
Quartz-crystal Microbalance Measurements of CD19 Antibody Immobilization on Gold Surface and Capturing B Lymphoblast Cells: Effect of Surface Functionalization
Icoz, Kutay; Soylu, Mehmet Cagri; Canikara, Zeynep; Unal, Ekrem (WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, 2018)We have investigated different surface functionalization methods to immobilize CD19 antibody on gold surface to capture B lymphoblast cells associated with the acute lymphoblastic leukemia disease. Quartz Crystal Microbalance ... -
Respiration monitoring using a paper-based wearable humidity sensor, a step forward to clinical tests
Solak, İrfan; Gençer, Serife; Yıldırım, Beyza; Öznur, Emine; Hah, Dooyoung; Icoz, Kutay (ELSEVIER, 2023)Monitoring respiratory variables can provide valuable information for clinical applications and sport activities. Paper-based wearable respiration monitoring systems have great advantages and potential, they are ... -
Simple Staining of Cells on a Chip
Kosker, Fatma Betul; Aydin, Omer; Icoz, Kutay (MDPI, 2022)Simple staining of cells is a widely used method in basic medical diagnostics, education, and research laboratories. The stains are low-cost, but the extensive consumption results in excessive toxic waste generation. Thus, ...